Endocrine Abstracts

Introduction: Peripheral arterial disease (PAD) is increased associated with an accumulation of patients with end stage kidney disease and diabetes. Recently, the cardio-ankle vascular index (CAVI) has been developed as an index reflecting the stiffness of the aorta independently of blood pressure. The aim of this study was to assess the prevalence of PAD in hemodialysis patients with diabetes.Methods: To examine the usefulness of CAVI to screen for the ...

We present a case of severe malignant pheochromocytoma complicated with intestinal pseudo-obstruction, which was refractory to conventional therapies but reacted to intravenous administration of an α-blocker, phentolamine.Malignant pheochromocytoma typically metastasizes to bones, liver, lungs, and lymph nodes, and average 5-year survival rate in the patient with metastases is approximately 50%. Treatment options for malignant pheochromocytoma inclu...

Introduction: Pheochromocytoma (PHEO) is a rare tumor of chromaffin cells with variable clinical presentation. Adrenal PHEOs secrete excessive amounts of noradrenaline or of noradrenaline plus adrenaline, whereas extra-adrenal PHEOs (paragangliomas) mostly secrete noradrenaline alone due to lack of expression of phenylethanolamine-N-methyltransferase (PNMT), the key enzyme converting noradrenaline into adrenaline. We report two exceptional cases of paragangliomas responsible f...